Research Journal of Pharmacy and Technology

Khairil Azwan ¹, Resni Mona ¹, Jannathul Firdous ², Dina Keumala Sari ³, Pamela Rosie David ⁴, Noorzaid Muhamad ¹

Affiliations
1 Cluster for Integrative Physiology and Molecular Medicine (CIPMM), Faculty of Medicine, Royal College of Medicine Perak, Universiti Kuala Lumpur, Jalan Greentown, 30450 Ipoh, Perak,, MY
2 ,Cluster for Integrative Physiology and Molecular Medicine (CIPMM), Faculty of Medicine, Royal College of Medicine Perak, Universiti Kuala Lumpur, Jalan Greentown, 30450 Ipoh, Perak,, MY
3 Nutrition Department, Faculty of Medicine, Universitas Sumatera Utara,, ID
4 Department of Anatomy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur,, MY

Abstract

Metabolic syndrome is a grouping of several medical conditions plaguing the modern world today. Excessive visceral fat is strongly associated with abdominal obesity which is one of the characteristics of metabolic syndrome. In general, an unbalanced, rich diet plays an important role in the proliferation of adipocytes. Our aim is to observe which diet contributes to the deposition of visceral fat such as the mesenteric fat. For eight weeks, thirty-five Sprague Dawley rats were divided into five groups and were fed five different types of diets. The five diets are normal rat chow, high sugar, high starch, high protein and high fat rat (palm oil-based) feed formula. Besides the formularized rat feeds, the rats were given tap water ad libitum. The result showed high fat diet promotes mesenteric fat proliferation when compared to other rat feed formula. Present study showed that high-fat diet promotes mesenteric fat proliferation when compared to other diets.

Keywords

Diet, Enzymes, High-fat, Mesenteric fat, Palm oil.

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